While the original team left House's direct supervision, they remained part of the show's world: Foreman eventually returned to the hospital to supervise House, while Chase and Cameron took positions in surgery and the ER.
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Without his "safety net" team, House was forced to confront his own loneliness and dependency. While the original team left House's direct supervision,
Season 4 kicks off with a literal vacancy. Foreman, Chase, and Cameron have left the building (Foreman quit, Chase was fired, Cameron resigned). House, who despises change, finds himself in a nightmare: he has to interview 40 new doctors to fill three slots. If you share with third parties, their policies apply